The Potential Dangers of Sucralose (Splenda): "How it is Manufactured Sucralose is produced by chlorinating sugar (sucrose). This involves chemically changing the structure of the sugar molecules by substituting three chlorine atoms for three hydroxyl groups.
History Sucralose was discovered in 1976 by researchers working under the auspices of Tate & Lyle Ltd., a large British sugar refiner. In 1980, Tate & Lyle arranged with Johnson & Johnson, the world's largest health care company, to develop sucralose. Johnson & Johnson formed McNeil Speciality Products Company in 1980 to commercialize sucralose.
In 1991, Canada became the first nation to approve the use of sucralose.
In April, 1998 the US Food and Drug Administration granted approval for sucralose to be used in a variety of food products (CLICK HERE for complete list of products using sucralose). Diet RC cola was the first US product with sucralose, introduced in May 1998.
Sucralose is not yet approved for use in most European countries, where it is still under review."